The use of carbohydrate loading drinks prior to surgery

Pre-operative carbohydrate loading
Fasting, typically nil-by-mouth from midnight before surgery was introduced to reduce the risk of pulmonary aspiration. However, the European Society for Parenteral and Enteral Nutrition (ESPEN) and NICE state that allowing patients to eat up to 6 hours prior to surgery and being able to drink appropriate fluids up to 2 hours before surgery is safe ^{7, 6}, enabling the patient to enter surgery in a fed state.

Carbohydrate loading before surgery has the following potential benefits:

Helps prevent dehydration^{8, 9}
Helps prevent catabolism, insulin resistance, muscle loss, weakness and fatigue and may also reduce the patient’s anxiety and improve comfort ^{2, 4, 10, 11, 12}
Promotes gut function^{2, 1}

Preload™ is a neutral-tasting carbohydrate loading drink mix specifically designed for use before elective surgery. Preload is presented in 50g pre-measured sachets which when added to water produces a solution with low osmolality.

A focus on nutrition to aid recovery after surgery

Providing optimal nutrition in the days following the operation is important to aid recovery. Pro-Cal shot^™ is a high calorie, low volume supplement which can be given post-operatively. A clinical trial regarding the use of Pro-Cal shot in postoperative patients showed a significant improvement in total daily oral calorie intake and a decreased postoperative hospital stay ¹³.
The following websites provide further information regarding nutrition and surgery:

Kehlet H (2005). Fast track colonic surgery: status and perspectives. Recent Results cancer Res 165: 8-13.
Noblett SE, Watson DS et al. Pre-operative oral carbohydrate loading in colorectal surgery: a randomized controlled trial. Colorectal Disease (2006); 8: 563-9.
Nygren J, Thorell A, Ljungqvist O. Pre-operative oral carbohydrate nutrition: an update. Current opinion Clin metabolic care 2001: 4: 255-9.
Ljungqvist O, Nygren J, Thorell A. Modulation of post-operative insulin resistance by pre-operative carbohydrate loading. Proc Nutr Soc (2002); 61 (3): 329-36.
Delgado-Rodriguez M, Bueno-Cavanillas A, Lopez-Gigosos R et al. Hospital stay length as an effect monifier of other risk factors for nosocomial infections. Eur J Epidemiol 1990; 6: 34-9.
National Institute for Health and Clinical Excellence (NICE) (2006). Clinical Guideline 32: Nutrition Support in Adults.
Weimann A, Braga M, Harsanyi L, Laviano A, Ljungqvist O, Soeters P; DGEM (German Society for Nutritional Medicine), Jauch KW, Kemen M, Hiesmayr JM, Horbach T, Kuse ER, Vestweber KH; ESPEN (European Society for Parenteral and Enteral Nutrition). ESPEN Guidelines on Enteral Nutrition: Surgery including organ transplantation. Clinical Nutrition (2006); 25:224-244.
Lobo DN, Bostock KA, Neal KR, Perkins AC, Rowlands BJ, Allison SP. Effect of salt and water balance on recovery of gastrointestinal function after elective colonic resection: a randomised controlled trial. Lancet (2002); 359 (9320): 1812-18.
GIFTASUP (2011). British consensus guidelines on intravenous fluid therapy for adult surgical patients. Available online at : http://www.bapen.org.uk/pdfs/bapen_pubs/giftasup.pdf
Yuill KA, Richardson RA, Davidson HI, Garden OJ, Parks RW. The administration of an oral carbohydrate containing fluid prior to major elective upper gastrointestinal surgery preserves skeletal muscle mass postoperatively – a randomised clinical trial. Clin Nutr (2005) 24 (1):32-7.
Thorell A, Nygren J, Ljungqvist O. Insulin resistance: a marker of surgical stress. Curr Opin Clin Nutr Metab Care (1999); 2: 69-78.
Henrikson M, Hansen H, Dela F. Preoperative feeding might improve postoperative voluntary muscle function. Clin Nutr (1999); 18 (Suppl 1): 82.
Sharma M, Wahed S et al. A randomized, controlled trial comparing standard post-operative diet with low volume high calorie oral supplements in colorectal patients. Presented at ASCRS Annual meeting 2011.

Our carbohydrate loading drink

Preload™

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