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SMA® Alfamino®

Hypoallergenic (non-allergenic) amino acid formula for the dietary management of severe cows’ milk allergy (CMA) and/or multiple food protein allergies (MFPA)1-4

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Product Description

SMA® Alfamino® is designed to provide first-line formula relief from the symptoms associated with severe CMA and/or MFPA.1-4 It can also be used in the dietary management of those infants who experience no symptom improvement on extensively hydrolysed formulas (eHFs).1,2,4


SMA® Alfamino® is nutritionally complete from birth and supplementary feeding from 6 months to 3 years of age and formulated to support growth, tolerance and absorption in the most challenging allergy conditions.1–3


For more information on SMA Alfamino® or cows' milk allergy:

  • Visit our CMA information page
  • Contact your local representative
  • Contact our Careline on 0800 0 81 81 80
Ingredients

Ingredients

Glucose Syrup, Vegetable Oils (Sunflower, Rapeseed, structured palm oil), Amino Acids (L-Arginine, L-Leucine, L-aspartic, L-aspartic acid, L-Lysine, L-Proline, L-Glutamine, L-Valine, Glycine, L-Isoleucine, L-Threonine, L-Serine, L-Phenylalanine, L-Tyrosine, L-Histidine, L-Alanine, L-Cystine, L-Tryptophan, Magnesium, L-Methionine), Medium Chain Triglycerides, Starch, Minerals (Calcium Glycerophosphate, Potassium Chloride, Calcium Citrate, Sodium Citrate, Potassium Citrate, Sodium Phosphate, Magnesium Oxide, Ferrous Sulphate, Zinc Sulphate, Copper Sulphate, Potassium Iodide, Manganese Sulphate, Sodium Selenate), Emulsifier (E472c), Schizochytrium sp. (DHA), Mortierella Alpina Oil (ARA), Vitamins (C, E, Niacin, Pantothenic Acid, A, K, Folic Acid, D, B12, Biotin), Acidity Regulator (E330), Taurine, Myo Inositol, Carnitine, Riboflavin, Thiamin.
Presentation

Presentation

400g tin (with a 4.4g scoop).

Precautions

  • Use under strict medical supervision after full considerations of all the feeding options available, including breastfeeding.
  • For oral or enteral use only.

Important Notice


A food for special medical purposes. Mothers should be encouraged to continue breastfeeding even when their infants have cow's milk protein allergy. This usually requires qualified dietary counseling to completely exclude all sources of cow's milk protein from the mothers’ diet. If a decision to use a special formula intended for infants is taken, it is important to give instructions on correct preparation methods, emphasising that unboiled water, unsterilised bottles or incorrect dilution can all lead to illness. Formula for special medical purposes intended for infants must be used under medical supervision. For healthcare professionals only.

prep1

Preparation Guidelines

The standard dilution of 13.3% is made by adding 1 level scoop of Alfamino® (approx 4.4g) to 30ml of water (approx 1 fluid oz). Incorrect storage, handling, preparation and feeding can eventually lead to adverse effects for the health of a baby.


  1. Wash hands well.
  2. Wash bottle, teat and cap
  3. Sterilise equipment (by boiling for 5 minutes or with a cold water sterilising solution).
  4. Boil drinking (tap) water. Allow to cool for no more than 30 minutes.
  5. Pour exact amount of water (see feeding table), into the sterilised bottle, carefully to avoid scalds, the water is hot.
  6. Add exact number of level scoops for age of baby
  7. Place the sterilised teat and cap on the bottle and shake well until powder is fully dissolved. Cool bottle under cold running water until lukewarm. Test the temperature by shaking a few drops onto the inside of your wrist
  8. Close tin tightly after each use and store in a cool dry place.
children

Usage Recommendations

Feeding Table Quantity per meal
Age of Infant Water (ml) No. of scoops* Meals Per Day
1-2 weeks 90 3 6
3-4 weeks 120 4 5
2nd month 150 5 5
3-4 months 180 6 5
5-6 months 210 7 5
From 5th (7th) month** 210 7 3-4

* Note: Use only the enclosed scoop.

** A healthcare professional should be consulted before introducing other food to a baby’s diet.

Product Storage and Shelf Life

Store in a cool dry place.

Shelf life of 24 months from date of manufacture.

Use within 3 weeks of opening.

Image 1 - Efficacy_Alfamino

Severe Symptom Management
SMA® Alfamino® is designed to relieve symptoms in infants with severe CMA and multiple allergies1,2

Image2-Gut_Alfamino

Supports Digestion and Malabsorption
SMA® Alfamino® has a low osmolarity and is the only AAF formulated with both MCTs and structured lipids to help support digestion and malabsorption5–7

Image3-Taste_Alfamino

Preferred Taste of SMA® Alfamino®
SMA® Alfamino® has preferred taste over competitor AAF formulas which may help feeding acceptance and health economic savings8,9

Alfamino® met the AAP hypoallergenicity criteria in a randomised, controlled trial and can be recommended for the dietary management of CMA:1
Alfamino_efficacy
Added MCTs
SMA® Alfamino® contains added medium-chain triglycerides for easily absorbed energy6

Structured Lipids
SMA® Alfamino® is the only amino acid formula to contain structured lipids†, which may support softer stools and both calcium and fat absorption5,7

Lowest Osmolarity
SMA® Alfamino® has the lowest osmolarity of any amino acid formula in the UK which may help to manage diarrhoea7
Product Product Format PIP Code Nestlé Line Code Case Size
SMA® Alfamino® 1*400g Tin 385-6416 12294404 6
Image1-weaning_guide.1

Weaning Guide
The SMA® Althera® and SMA® Alfamino® weaning guide can be downloaded here.


Image2-SmilesBack.1

Smilesback
The SmilesBack mobile app allows parents to keep track of their baby’s symptoms and feeds to support healthcare professionals diagnose or manage CMA. Learn more here.


Image3-comiss-thumbnail.1

ComissTM
The CoMiSSTM awareness tool can be used by healthcare professionals to quantify CMA symptoms. Learn more here.

*ACBS approved. SMA® Alfamino® is for complete nutritional support from birth or supplementary feeding from 6 months and up to 3 years of age for the dietary management of cows’ milk allergy and/or multiple food allergies.

 

Per 100g as sold

Per 100ml (standard 13.8% dilution)

General

 

 

Energy kJ /kcal

2093 /500

278 /66

Fat g (44% kcal) of which:

24.6

3.3

saturates g

8.5

1.1

MCT g

6.0

0.80

monounsaturates g

9.4

1.2

polyunsaturates g

5.2

0.69

Carbohydrate g (45% kcal) of which:

56.3

7.5

sugars g

4.0

0.53

Protein g (11% kcal)

13

1.8

Salt = Na (g) x 2.5 g

0.49

0.065

Vitamins

 

 

A µg

500

66

D µg

12

1.7

E µg

11.0

1.5

K µg

45

6.0

C mg

80

11

Thiamin mg

0.51

0.068

Riboflavin mg

1.0

0.13

B6 mg

0.40

0.053

Niacin mg/mg NE

7.0/12

0.93 /1.6

Folate µg DFE

125

17

Folic acid µg

75

10

B12 µg

1.5

0.20

Pantothenic acid mg

3.3

0.44

Biotin µg

12

1.6

Minerals

 

 

Sodium mg/mmol

195/8.5

26/1.1

Chloride mg/mmol

420/12

56/2

Potassium mg/mmol

570/15

76/2.0

Calcium mg/mmol

530/13

70/2

Phosphorus mg

350

47

Phosphate mmol

11

1.5

Magnesium mg/mmol

45/1.9

6.0/0.2

Iron mg

5.0

0.66

Zinc mg

5.0

0.66

Copper mg

0.43

0.057

Iodine µg

110

15

Selenium µg

26

3.4

Chromium µg

<50

-

Molybdenum µg

<70

-

Manganese mg

0.068

0.009

Fluoride mg

<1.0

-

Other nutrients

 

 

DHA mg

135

18

ARA mg

135

18

α-Linolenic acid mg

400

53

Linoleic acid mg

4000

532

Taurine mg

40

5.3

L-Carnitine mg

8.5

1.1

Choline mg

145

19

Inositol mg

35

4.7

Osmolarity

294 mOsm/L

Osmolarity

327 mOsm/kg

NE - Niacin Equivalent
TE - Tocopherol Equivalent
DFE - Dietary Folate Equivalent
DHA - Docosahexaenoic acid
ARA - Arachidonic acid

Frequently asked questions

SMA® Alfamino® does not contain any cows' milk, soy or coconut.
Studies have shown that infants fed a formula containing structured lipids† vs. those on a standard infant formula have had improved bone mineral density and calcium absorption, softer stool consistency and reduced crying time.4 Structured lipids† unique structure is designed to mimic the composition of breastmilk and is rare in standard vegetable oils. They are less likely to form insoluble soaps which are more likely to be malabsorbed, reducing calcium and fat absorption and producing uncomfortable, harder stools.5

You can learn more about cows' milk allergy on our condition pages, here.

References:
  1. Nowak-Wegrzyn A et al. Clin Pediatr 2015; 54(3): 264–272.
  2. NHSc, Clinical Audits & Service Reviews: Leeds General Infirmary & Manchester Children’s hospital. Data on file.
  3. Corkins M et al. Pediatrics 2016; 10: 3–9.
  4. Luyt D et al. Clin Exp Allergy 2014; 44: 642–672.
  5. Bar-Yoseph F et al. Plefa 2013; 89(4): 139–143.
  6. Marten B et al. International Dairy Journal 2006; 16: 1374–1382.
  7. Nutritional information from product datacards: Puramino®, Neocate LCP® and Neocate Syneo®. June 2018.
  8. Data on file. Alfamino® vs Puramino® and Neocate LCP®
  9. Maslin, K. et al. Pediatr Allergy Immunol 2018; 29(8): 857–862.

Footnotes and abbreviations:
AAF, amino acid formula
CMA, cows’ milk allergy
eHF, extensively hydrolysed formula
FAQs, frequently asked questions
MCTs, medium-chain triglycerides
MFPA, multiple food protein allergies

Nestlé Health Science produces a range of foods for special medical purposes (FSMP) for use under medical supervision. A sample product should only be requested for a patient if deemed suitable following a professional evaluation from an appropriate healthcare professional. Althera® and Alfamino® are infant FSMPs and should only be used after the full consideration of the feeding options available, including breastfeeding.
The Nestlé Health Science Sample Service is available to healthcare professionals only, who require sample products for professional evaluation when they have no sample product or if a patient has insufficient product to cover their needs. This service is not intended as a long term solution for a patient.
® Reg. Trademark of Société des Produits Nestlé S.A. Terms and conditions apply.

IMPORTANT NOTICE: Mothers should be encouraged to continue breastfeeding even when their babies have cows' milk protein allergy. This usually requires qualified dietary counselling to completely exclude all sources of cows' milk protein from the mothers’ diet. If a decision to use a special formula intended for infants is taken, it is important to follow the instructions on the label. Unboiled water, unboiled bottles or incorrect dilution can make babies ill. Incorrect storage, handling, preparation and feeding can eventually lead to adverse effects on the health of babies. Formula for special medical purposes intended for infants must be used under medical supervision.

Nestlé Health Science UK Statement on Demand for Specialist Infant Formulas for Cows’ Milk and Multiple Food Allergies

Read the full statement


We believe breast milk is the best food for infants. When in consultation with their healthcare professional, mothers and families find that optimal breastfeeding is not possible due to their infant’s medical condition, formulas for special medical purposes play a vital role in providing essential nutrients to infants. We have a global commitment to market breast-milk substitutes responsibly.


This website is about the management of cows’ milk protein allergy and nutritional solutions intended for infants. By continuing on this website, you accept that Nestlé Health Science supplies the information at your own request.


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