HCP

OUR RANGE OF HYPOALLERGENIC NUTRITIONAL SOLUTIONS: ALTHÉRA® AND ALFAMINO®


Nestlé Heath Science's Althéra® and Alfamino® have been developed to help meet the growth and development needs of infants and children with food allergies and intolerances.1,2


Nutritional solutions for the management of cows' milk allergy (CMA)


There are two types of formulas recommended for the management of CMPA: extensively hydrolyzed formulas and amino acid-based formulas

Following diagnosis, CMA is managed through the complete removal of cows' milk proteins (CMPs) from the infant’s diet. CMA can also occur among exclusively breastfed infants. When an exclusively breastfed infant is diagnosed with CMA, the mother must exclude all CMP from her diet.3


Mothers should be encouraged to continue breastfeeding, but in case this is not an option, specialist infant formulas are available for infants and young children with CMA to reduce or completely remove the allergenic potential.3 These formulas contain the nutrients to help support healthy infant growth and development.1,2 There are two different types of formulas for the management of CMA:


Extensively hydrolysed formulas,* or “eHFs,” in which CMPs have been extensively hydrolysed into peptides. As a result, they are less allergenic than whole milk formulas and are well tolerated by most children with cows' milk or soy protein allergies.3-5


Amino acid-based formulas (AAFs) contain free amino acids, which are non-allergenic. They are recommended when an extensively hydrolysed formula is not tolerated or as first-line dietary management when the baby has extremely severe or life-threatening allergic symptoms (anaphylaxis or immediate type reactions).3-5


*Note: Partially hydrolysed formulas (pHFs) are also sometimes referred to as hypoallergenic; however, pHFs are not intended for dietary management of diagnosed CMA.

CHOOSING THE RIGHT NUTRITIONAL SOLUTION


Mothers should be encouraged to continue breastfeeding, however if this is not an option, this decision tree will help you to consider the possible options for your patients based on their symptoms and will help you in selecting the right solution at the right time.


Choosing the right nutritional solution for cow’s milk allergy

SAFETY BY DESIGN
HYDROLYSIS OF PROTEINS TO REDUCE ALLERGENICITY IN EHFS
IMPORTANCE OF LACTOSE IN INFANTS’ DIET
IMPORTANCE OF TASTE AND TASTE DEVELOPMENT

REFERENCES

  1. Niggemann B, et al. Safety and efficacy of a new extensively hydrolyzedhydrolysed formula for infants with cows’ milk protein allergy. Pediatr Allergy Immunol. 2008;19(4):348–54.
  2. Nowak-Wegrzyn A, et al. Evaluation of hypoallergenicity of a new, amino acid-based formula. Clin Pediatr (Phila). 2015;54(3) 264–72.
  3. Luyt D et al. BSACI Milk allergy guideline. Clinical & Experimental Allergy. 2014 (44) 642–672. 2008;19(4):348–54.
  4. Venter C et al. Clinical and Translational Allergy. 2013;3:23.
  5. NICE. Cows' milk protein allergy in children NICE CKS. 2015 Available at: https://cks.nice.org.uk/cows-milk-protein-allergy-in-children#!scenario:1 [Accessed Nov 2017].
  6. Rapp M, et al. Characterization of an extensively hydrolyzedhydrolysed whey infant formula with a low bitterness. Clin Transl Allergy. 2013; 3(3): P132.
  7. Infant nutrition and feeding. A guide for use in the WIC and CSF programs. March 2009:14.
  8. Francavilla R, et al. Effect of lactose on gut microbiota and metabolome of infants with cow’s milk allergy. Pediatr Allergy Immunol. 2012;23(5):420–7.
  9. Data on file. 2018.
  10. Meyer, R. et al. EMJ Allergy and Immunol. 2017; 2(1): 46–51.
  11. Nutten S, et al. Abstract. EAACI Congress, 26-30 May, 2018.

 

IMPORTANT NOTICE: Mothers should be encouraged to continue breastfeeding even when their babies have cows' milk protein allergy. This usually requires qualified dietary counselling to completely exclude all sources of cows' milk protein from the mothers’ diet. If a decision to use a special formula intended for infants is taken, it is important to follow the instructions on the label. Unboiled water, unboiled bottles or incorrect dilution can make babies ill. Incorrect storage, handling, preparation and feeding can eventually lead to adverse effects on the health of babies. Formula for special medical purposes intended for infants must be used under medical supervision.